ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will increase the level or outcome of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Acute ergot toxicity characterised by vasospasm and tissue ischemia has long been related to coadministration of ritonavirdronedarone will boost the degree or influence of